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High-risk groups include individuals with functional or anatomic asplenia, HIV infection, leukemia, lymphoma, Hodgkins disease, multiple myeloma, generalized malignancy, chronic kidney failure, nephrotic syndrome, or other immunosuppressive conditions

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[1] This multifaceted approach leads to reduced caloric intake and subsequent weight loss

However, as with any WL intervention, there will be heterogeneity in treatment responses, even with the new molecules for obesity treatment [15]