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BMI of 30 or higher (obesity) BMI of 27 or higher with at least one weight-related condition (hypertension, high cholesterol, sleep apnea, Type 2 diabetes, or cardiovascular disease) Prior difficulty maintaining weight loss through diet and exercise alone No contraindicated medical history (reviewed at consultation) Commitment to regular monitoring and follow-up visits Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Prior serious hypersensitivity reaction to semaglutide or excipients Current pregnancy or active breastfeeding Certain pancreatic conditions (evaluated at consultation) Not sure if you qualify

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The bacterial growth risk is secondarypeptide degradation is the primary failure mode

Both patients and animal models show reduced intestinal fungal diversity and an increased abundance of potentially pathogenic taxa, particularly Candida albicans (Jangi et al., 2024