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This is due to various factors, including poor diets, malabsorption of vitamins, and certain medical conditions and medications which can contribute to lower levels of vitamin B12 in the body

A randomized controlled trial published in the World Journal of Gastroenterology demonstrated that vitamin C supplementation reduced markers of oxidative stress and inflammation in patients with Crohn's disease, highlighting its role in mitigating gut inflammation and improving clinical outcomes (Meyer et al., 2019)

Mitochondria, as the primary source of ROS in mammalian cells, are particularly vulnerable, with oxidative stress contributing to mitochondrial dysfunction, energy depletion, and cell death (Cui et al., 2012)

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