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Oxidative phosphorylation modulators By competitively inhibiting long-chain 3-keto-CoA sulfatase, trimetazidine shifts myocardial metabolism from fatty acid -oxidation to glucose oxidation, thereby optimizing energy production during episodes of ischemia

These data were first presented by Nakul Ganju, MD, of Howard University Hospital, Washington, DC, at the 2026 Crohns and Colitis Congress on Friday, January 23, 2026, in Las Vegas, Nevada

doi: 10.1016/s0167-0115(99)00089-0

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