glp 1 shortage fda FDA's GLP-1 decision kicks off 'unprecedented' tussle over Eli Lilly's Mounjaro, Zepbound removed

doi: 10.1111/ijpo.12177 194 HorikawaYEnyaMKomagataMHashimotoKIKagamiMFukamiMet al

Pathologies of the haemolymphopoietic system Thrombocytopenia, leukopenia, anemia, agranulocytosis Immune system disorders Hypersensitivity reactions (urticaria, laryngeal edema, angioedema, anaphylactic shock) Nervous system disorders Dizziness Gastrointestinal disorders Gastrointestinal reaction Hepatobiliary pathologies Abnormal liver function, hepatitis Skin and subcutaneous tissue disorders Erythema multiforme, Stevens Johnson syndrome, Epidermal necrolysis, Skin rash Kidney and urinary disorders Acute renal failure, interstitial nephritis, hematuria, anuria

Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, et al

Tissues were homogenized using a Tenbroeck homogenizer in 50 mM K-phosphate buffer, pH 7.4, containing 0.25 M sucrose, 1 mM K-EDTA, and 0.1 mM dithiothreitol