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Description

Historically, perioperative guidelines and reviews have not advocated the discontinuation of GLP-1RAs prior to surgical procedures

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Initial assessment typically includes 24-hour urinary free cortisol measurement, late-night salivary cortisol testing, or low-dose dexamethasone suppression testing to confirm hypercortisolism

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The most common dose-related adverse effect is severe nausea and vomiting, which can escalate to dehydration and electrolyte imbalances

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