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Mechanism of Action: Same Biology as GLP-1 Drugs GLP-1 medications like Ozempic work by directly binding to GLP-1 receptors throughout the body in the brain, pancreas, and stomach producing sustained, maximal receptor activation that reduces appetite and regulates blood sugar
It is currently approved as an adjunct to lifestyle adjustments for weight management in obese and overweight patients with a weight-related comorbidity, such as dyslipidemia and hypertension [6]
Although GLP-1 drug manufacturers agreed to a $245 net price, a substantial discount off prevailing list prices, savings to plans from a lower price may have been insufficient to offset higher costs associated with an uptake in GLP-1 use for obesity treatment