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As an example, findings from a phase I clinical study on nabulizumab, an anti-PD-1 antibody for solid tumor treatment, indicated survival rates of 22.4 and 16.8 months for non-small cell lung cancer and renal cell carcinoma, respectively [115]

It was shown that aged or/and damaged RBCs are sequestrated in the hepatic sinusoid in a PS-dependent way, and the human sinonasal epithelial cells (HSECs) mediate the recognition and the binding of damaged RBCs in a PS-dependent manner via stabilin-1 and stabilin-2 (pro-phagocytic signals and ligandligand interactions) [275,276,277]