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However, taking extremely high doses may cause acne, rashes, or place stress on the kidneys in certain cases

However, it's important to contextualize this assessment within the limitations of the available evidence: most safety data comes from relatively small studies, often of short-to-moderate duration, conducted primarily in the Soviet Union, Russia, and Eastern Europe where methodological standards and reporting practices have sometimes differed from Western pharmaceutical trial requirements

Research published in Brain Communications highlights that those with Alzheimers disease and mild cognitive impairment often show reduced levels of glutathione in critical brain areas, like the left hippocampus

Biomaterials, 2019, 188: 8395 Zhang G, Cheng W, Du L, et al