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Eligibility, medication selection, and dosing are determined solely by the clinician, following established medical protocols

For the next few weeks, the drug took a toll on her mental and physical health

reported outcomes are more plausibly indirect via recovery, routine adherence, and activity changes

However, under conditions of stress and inhibition of the electron transport chain, the enzyme works in the opposite direction by transferring electrons from NADPH to NAD + , which impairs mitochondrial antioxidant defenses and feeds more reducing equivalents into the impaired electron transport chain leading to increased electron leakage and superoxide formation [133]