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Anything that disrupts the normal homeostasis or stability of neurons can trigger hyperexcitability and seizures

Green tea catechins inhibit microglial activation which prevents the development of neurological disorders

Ramzan R, Dolga AM, Michels S, Weber P, Culmsee C, Rastan AJ

High levels of catecholamine metabolism in the midbrain are associated with increased levels of neuromelanin in the same region and, it is neuromelanin that is thought to be one of the molecules responsible for inducing chronic neuroinflammation in PD