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ALSO INCLUDED Coaching and lifestyle support Free Discord community with a psychologist-led health-coaching channel open to anyone

Ultimately, 706 participants met the eligibility criteria and were randomly assigned to one of several treatment arms: once-weekly subcutaneous injections of Cagrilintide at doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo

Cholecystectomy was performed more frequently in liraglutide-treated patients (HR 1.56) but for similar proportions of the patients who experienced gallbladder- or biliary tractrelated events (57% with liraglutide vs

Data collection and refinement statistics are summarized in Supplementary Table S1