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The mechanisms of antidiabetic action of this unique class of compounds may be diverse and include: insulin-mimetic action, ability to inhibit specific enzymes ( -amylase, glucosidase, aldose reductase), antioxidant activity, and the ability to regulate hypo/hyperglycemia ( In vivo studies on mice have shown that the terpene compound stevioside and its derivatives can mimic insulin

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J., Kim, Y.-H

A total of 120 patients with infrainguinal arterial disease and Rutherford 56 foot gangrene were enrolled and divided into two groups: 60 received alprostadil post-IR, and 60 served as controls