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The electron transfer from NADH+ and FADH+ to NAD and FAD by complexes 1 and 4 produce O 2 radicals which are then converted into H 2 O 2 enzymatically by the catalytic activity of SOD

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Concluding remarks In this review, we have summarized the mechanisms through which redox signaling pathways regulate human diseases as well as the current clinical potential of therapeutic strategies

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