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Nearly all G6PD pathogenic variants are single nucleotide missense variants resulting in the substitution of a single amino acid

M36008)

Mice treated with GHK showed little learning impairment after sleep deprivation in line with saline-treated mice that were not sleep deprived, and significantly less than sleepdeprived mice treated with saline (Figure 1)

Two key parameters were measured: occupancy, defined as the percentage of frames in the trajectory where any cholesterol molecule is within the cutoff distance from the receptor, and interaction residence time, defined as the time that a cholesterol molecule remains in the binding site, providing information about the strength of the interaction (full data included in Supplementary Tables 1 and 2)