However, this large number warrants important context: 35 of the 36 studies included in the systematic review were preclinical (conducted in laboratory or animal models), and only one clinical study met the review's inclusion criteria
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Feron, O., Dessy, C., Moniotte, S., Desager, J
They are often sufficient for correcting mild dietary deficiencies (e.g., in vegans who dont consume fortified foods) and can sometimes be used for maintaining levels after an initial course of injections, provided absorption is adequately monitored by a healthcare professional