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sCSD and sB suppress IL-22-induced STAT3 activation in CAV-1 silenced keratinocytes Because STAT3 is involved in keratinocyte proliferation and affects the expression of several cytokines 13 and CAV-1 downregulation induces STAT3 activation in keratinocytes 6 , we examined whether STAT3 activation is targeted by versions of CSD

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This was followed by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis and immunoblotting