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in its approved obesity indication semaglutide 2.4 mg once weekly produced roughly 15% mean weight loss over 68 weeks in STEP 1 [5]

Staresinic M, Sebecic B, Patrlj L, et al.: Gastric pentadecapeptide BPC 157 accelerates healing of transected rat achilles tendon and in vitro stimulates tendocytes growth

Table: Comparing the Major GLP-1 Receptor Agonist Drugs To summarize the key characteristics of the GLP-1 drugs up to this point (prior to semaglutide), the table below compares their properties: Table 2: Comparison of GLP-1based therapies

Equally important is a thorough regulatory due diligence at the pre-market stage, as gaps in product characterisation, safety data, or substantiation strategy can significantly increase the risk of costly delays, requests for additional information, or ultimately a negative regulatory outcome