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Semaglutide cons Side effects : The main drawbacks of semaglutide are possible stomach-related side effects like nausea, diarrhea and vomiting, which can be bothersome for some people

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In expanded populations, comparing semaglutide versus sitagliptin for the composite outcome of myocardial infarction or stroke yielded a hazard ratio of 0.82 (95% confidence interval (CI) 0.74 to 0.91), and comparing tirzepatide versus dulaglutide for the composite outcome including mortality yielded a hazard ratio of 0.87 (95% CI 0.75 to 1.01)