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On average, patients maintain 50% of their weight loss after five years

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The GLP-1 receptor sits in multiple brain regions responsible for mood regulation, including the amygdala and prefrontal cortex, meaning medication that targets these pathways can theoretically influence emotional tone

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S.et al (2024b)

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By week 23, subtle changes often become visible: clothes fit differently, water retention may decrease, and energy levels sometimes shift

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