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This study also identified the depletion of the purine metabolite, hypoxanthine, in chronic fatigue patients (according to Canadian Consensus criteria) which may impair ATP production and contribute to the biochemical changes associated with PEM

Sex differences in the composition of weight gain and loss in overweight and obese adults

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These results suggested that the Glp1r , Htr4 , Ntsr1 , Nos1 , and Ntrk1 genes were novel DEGs in the combination group, whose expression levels did not reach the DEG status in either the (-)-Vestitol group or the Salviolone group