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It may also affect anti-inflammatory signalling and extracellular matrix regulation

Some medical professionals studying this matter think that a rapid change in blood sugar levels could be the reason for the vision complications (according to a 2025 study)

ACE2 siRNA hMECs were plated (8090% confluent) and cultured for 24 h in growth medium (Endothelial Cell Growth Medium MV 2 supplemented with growth factors and 5% antibiotics)