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The interactions within the TVS, immune cells, and ongoing neurogenic or neuroinflammatory responses play significant roles in migraine pathophysiology, potentially leading to the establishment of chronic maladaptive pain

Dysregulation of this pathway can bias TRP metabolism toward neurotoxic and pro-inflammatory metabolites, thereby amplifying excitotoxicity, oxidative stress, and immune-driven disturbances in glutamatergic and monoaminergic neurotransmission

The dizziness on semaglutide that some users experience often relates to blood sugar fluctuations caused by irregular eating

Stereotaxic injections LepRb-Cre mice were anesthetized with isoflurane (1.52.0%, 1 L/minute in O 2 ) and placed in a stereotaxic frame (Kopf Instruments, Tujunga, CA)