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Semaglutide primarily works by activating the GLP-1 receptor, which helps regulate appetite, satiety, food noise, gastric emptying, and blood sugar-related signaling

Lilly spokesperson Kristiane Silva Bello said her company was "deeply concerned" about "serious health risks" from compounded drugs that "should not be on the market." Yet marketed they are

Krohne TU, Hunt S, Holz FG

Future investigations should leverage the pleiotropy of GLP-1RAs to evaluate their effectiveness in treating multimorbidities, rather than focusing on a single health condition, particularly where obesity or other mechanistic pathways affected by GLP-1RAs are leading drivers, the authors write in their paper