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WO2023/061978A1

Most people inject retatrutide once per week on the same day

People with very high baseline A1C and long-standing diabetes Those with pre-existing diabetic retinopathy or macular edema Patients taking insulin therapy at the same time Anyone experiencing large and rapid A1C reductions over a short period People with additional vascular risks such as high blood pressure, high cholesterol, kidney disease, or sleep apnea Many patients notice blurred vision or trouble focusing on close objects when they first begin semaglutide therapy

There have been no spontaneous reports of opportunistic infections associated with saxagliptin use