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2021;270:113704 Elsevier

Regulation of T-cell signaling by post-translational modifications in autoimmune disease

In the Phase 2 trial, the cohorts that escalated to higher maintenance doses began at 2mg weekly and increased by 2mg every 4 weeks

5.6 Limitations of direct administration and the rationale for delivery systems In moving from laboratory findings to clinical applications, one critical bottleneck is the limited effectiveness of direct administration of therapeutic agents such as probiotics, 6-gingerol, and vitamin D