These effects include promoting cell survival/proliferation, 52,53 migration/invasion, 53,54 oncogenic transformation, 55,56 and epithelial-to-mesenchymal transition, 54,57,58 as well as promoting tumor angiogenesis 59 and lymphangiogenesis 60 and enhancing a cancer stem cell-like phenotype
doi: 10.3390/nu13114025 429 TuSHChenLCHoYS
However, the G1 and G4 groups showed a reduction in the activities of this enzyme (35 and 42% respectively) suggesting that substantial concentrations may have been used up in the process of combating oxidative stress as a result of the diabetic condition
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