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These mechanisms suggest a coordinated regulation of key enzymes and signaling pathways involved in lipid synthesis and breakdown, such as AMPK and SREBP-1c, which are critical for maintaining hepatic lipid homeostasis (6)

Side effects are uncommon but may include slight redness or soreness at the injection site

That step up came with the FDA approval of a new GLP-1 receptor agonist called semaglutide, best known as a weekly injection to treat type 2 diabetes that is sold under the brand name Ozempic

GLP-1 drugs like Semaglutide demonstrated significant weight loss benefits for patients with a BMI over 40, making them a preferred option for managing high-risk obesity cases