is glutathione an enzyme Metabolism - overview glutathione peroxidase enzyme The family:

10.1126/science.1164382 211 PasiniB.StratakisC

Intranasal insulin has been investigated in a phase 2 trial in 31 PD participants (NCT04251585) showing acceptable safety but with efficacy data regarding cognitive endpoints yet to be published [164], and a combination of intranasal insulin and glutathione is currently investigated to improve verbal fluency in a phase 2 trial in PD subjects (NCT05266417)

Given that these basal metabolic processes are putatively present in both groups of this study and no indications exist that these could play a role in tinnitus pathophysiology, we surmise that this possible confounder can be ruled out in the presented results and the found differences between groups represent true effects

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