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Epigallocatechin gallate (EGCG) is a polyphenol used for various pathological treatments as it plays anti-inflammatory roles by blocking the activation of transcription factors of upstream inflammation-associated proteins, such as NF-B and activator protein-1 (AP-1)

When Yuyang Liu, a graduate student in his lab and first author of the study, compared SLC25A39s structure against others in the SLC family of transporters in the AlphaFold protein structure database, Liu spotted a unique extra loop in the protein

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