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In such cases, no treatment is generally required If required, a surgical excision and complete removal of the macule, primarily to address cosmetic issues may be undertaken Treatment of the underlying associated genetic disorder, if any Follow-up care with regular screening and check-ups are encouraged How can Melanotic Macules of Oral Mucosa be Prevented

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Thus, TRG is expected to break the dilemma of tumor drug resistance and improve chemotherapy efficacy