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Hyperinsulinemia amplifies androgen synthesis, OS disrupts granulosa mitochondrial competence and aromatase activity, and circadian misalignment perturbs gonadotropin timing

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DMSA chelation therapy increased lead excretion on average by a factor of 12 and rapidly reversed lead related symptoms (largely neurological and gastrointestinal) in a case series of 17 lead-poisoned adults [102]

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