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In research models, it is utilized to explore pathway-level dynamics, signaling activity, and system-level processes related to compound interactions and metabolic research environments

At pH 6.0, OATP2B1-mediated transport of atorvastatin and cerivastatin was not inhibitable, while rosuvastatin transport was inhibited by E-3-S, rifamycin SV and cyclosporine with IC 50 values of 19.73.3M, 0.530.2M and 2.20.4M, respectively

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