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Clinical Indicators: Objective data supporting GLP-1 need (e.g., A1C trends, weight loss, blood pressure)

Consistent with other GLP-1 agonists, orforglipron labeling is expected to include the standard boxed warning about thyroid C-cell tumors and a contraindication in patients with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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