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* Disminucin del riesgo de enfermedades cardacas y renales

Compared to young mice, old mice had cognitive impairment and many brain abnormalities such as glutathione deficiency, increased oxidative stress, impaired mitochondrial function, elevated inflammation, genomic damage and lower levels of brain-supporting factors

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Mutations as well as aging related modification of -crystallins that affect the structure, oligomerization and chaperone function, lead to decreased solubility and increased protein aggregation, making the lens prone to the development of congenital or senile cataracts (163)