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Consideration should be given to a slower rate of dose titration and a lower target dose in the elderly and in patients who are debilitated or who have a predisposition to hypotensive reactions [see Clinical Pharmacology (12.3)]
When estrogen is stable, it supports serotonin production and keeps emotional regulation on an even keel
This concern is more acute for people with type 2 diabetes who take other glucose-lowering medications alongside tirzepatide
These symptoms are linked to how the medication slows digestion, as seen with other GLP-1s
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