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If constipation persists beyond seven days despite fibre and fluids, hold the next step

You can take oral supplements or patches sleeping

doi: 10.1017/s0029665120006916 60 FujiwaraHDocampoMDRiwesMPeltierDToubaiTHenigIet al

Consult with your doctor before taking any extract of milk thistle, as there may be side effects or contraindications based on your specific health situation