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While these agents often spare normal proliferating tissues, they introduce new toxicity patternssuch as dermatologic reactions, QT prolongation, diarrhea, and hepatotoxicityoften linked to the pathways they target in normal tissues
[DOI] [PubMed] [Google Scholar] Yamazaki N, Yamanaka Y, Hashimoto Y, Shinohara Y, Shima A, Terada H
In this case, we likewise identified two pathogenic rare variants in the CFI gene associated with Factor I deficiency
While earlier GLP-1 drugs have decades of data behind them, newer high-potency agonists and multi-agonist combinations will require extended monitoring as their use expands
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