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Those with a personal or family history of thyroid tumors, Pancreatitis, or severe kidney or liver disease should also avoid this medication without consulting a doctor first

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Glucose-6-phosphate dehydrogenase is found in all cells and is responsible for the first reaction of the pentose phosphate pathway in which glucose-6-phosphate is oxidized to 6-phosphogluconolactone with concomitant production of NADPH