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Novel strategies have been developed recently to improve palatability and the release and absorption of butyrate in the digestive tract ( On the other hand, dietary fiber is used by some bacteria in the gut microbiota for butyrate production in two different ways: (I) Direct, where fiber acts as a substrate for bacterial fermentation producing butyrate, (II) Indirect since bifidogenic fibers help to increase the abundance of bifidobacteria, which increase butyrate production indirectly ( Maybe, the most efficient way to influence the composition of intestinal and colon microbiota is by ingestion of dietary fibers such as inulin-type fructans, xylooligosaccharides, arabinoxylans, arabinoxylan oligosaccharides, -glucans, and oligofructose ( A high-fiber diet can cause gastrointestinal discomforts, such as gas, bloating, and constipation in patients with Crohns disease, irritable bowel syndrome, or ulcerative colitis

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