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Dev Pharmacol Ther

In this context, recent studies have shown that in colostrum and mature milk, IL-2, IL-10, and IFN- are higher at night, while IL-6 and TNF- are higher during the day, exhibiting circadian rhythms

Crosstalk between the IGF signalling system and the steroid hormone receptor superfamily in endocrine-related cancers may be mediated through genomic or non-genomic signalling cascades that can be ligand dependent or independent, as displayed in Figure 4