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Abstract The lysyl oxidase family of enzymes (LOXs) catalyze oxidative deamination of lysine side chains on collagen and elastin to initialize cross-linking that is essential for the formation of the extracellular matrix (ECM)

The increased bone formation was attributed to larger bone dimensions and increased cortical cross-sectional area, as determined by in vitro measurements with peripheral quantitative computed tomography (pQCT) and Archimedes' principle