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In fibroblasts, the mannose-6-phosphate receptor pathway mediated uptake and delivery of -Gal A to the lysosomes, whereas, at least in the applied in vitro system, the mannose-6-phosphate receptor pathway did not mediate lysosomal delivery of -Gal A into endothelial cells

Este aumento del nerviosismo, puede afectar tambin al sueo, provocando insomnio y un descanso no adecuado

HIV-1 Tat-mediated microglial senescence by miRNA-505-SIRT3 pathway Senescence was initially defined as the cessation of cell division after multiple replication cycles [62] and has expanded to include premature senescence triggered by telomere shortening, oxidative stress, mitochondrial dysfunction, and lysosomal alterations [63]

J Pharmacol Exp Ther 1998