Bone Density and Healing IGF-1 has a significant positive effect on bone healing, which it exerts by stimulating the proliferation and differentiation of osteoblasts, supporting the regeneration of bone tissue after injury 29
AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (GPT-5, released 2025-08-07) was used to generate Figure 1 and the Graphical Abstract and to improve the readability and language of the manuscript
If confirmed in prospective studies, GLP-1RAs could represent the first medical therapy demonstrated to reduce rupture risk in observational data, offering a novel treatment option for patients with unruptured aneurysms who are not ideal surgical candidates due to smaller aneurysm size, older age, high surgical risk, or patient preference
Red flag #1: No real medical intake If the consult is the injector glancing at your face for ninety seconds and quoting a price, leave