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Obesity is one of the main risk factors for metabolic diseases such as diabetes and non-alcoholic fatty liver disease (NAFLD) and is often accompanied by abnormal mitochondrial function and mitochondrial quality control

Absolute bioavailability has been estimated to be between 64% and 90%

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In order to evaluate the impact of longer term, oral GSH supplementation on GSH status and in vivo oxidation status, this study performed the first randomized, double-blinded, placebo-controlled trial of orally administered GSH in healthy, adult humans