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While mild nausea, constipation, or loose stools are common when starting Wegovy, symptoms that interfere with daily activities or persist beyond a few days at each dose increase warrant medical attention

Liver slices contain hepatocytes, KCs and hepatic stellate cells, creating a multi-cellular environment

2.4 Delayed Gastric Emptying GLP-1 receptor agonists slow gastric emptying through: Reduced antral contractility Increased pyloric tone Modulation of vagal signalling This prolongs gastric distension, enhances satiety and contributes to reduced meal size