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Osteoblasts continue producing excessive osteoid with poor mineral quality, contributing to bone fragility and structural weakness (Maruotti et al., 2017)

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Lane 1: Molecular weight marker Lane 2: Cell pellet after sonication Lane 3: Supernatant after sonication Lane 4: Flow through after binding Lane 5: Wash Lane 6: Elution 1 Lane 7: Elution 2 Lane 8: Elution 3 Lane 9: Elution 4 Lane 10: Elution 5