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The pathogenesis of oral MA remains uncertain, although its clinical behavior is suggestive of a reactive origin

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While we need longer-term data for complete certainty, the proven benefits of major weight loss for cancer prevention likely outweigh any theoretical risks that havent appeared in current studies

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However, the heterologous expression of jr PPO1-wt attests that the decisive factor for enhancing the yield of enzymatically active and soluble PPO is low temperature (2026 C), especially in combination with a glutathione-S-transferase (GST) tag 21

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