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So they can only compound peptides that fall into five strict categories: FDA-approved peptides for human use (e.g., sermorelin) FDA GRAS (Generally Recognized as Safe) peptides (historical regulatory status) Peptides with a USP monograph (United States Pharmacopeia standard) Peptides on the FDA 503A Bulks List (official pre-approved list for compounders) Peptides in Category I of the interim 503A Bulks List (temporary pathway, under review) Nearly all peptides marketed for wellness, recovery, or longevity (as noted in regulatory guidance from Frier Levitt legal authority on peptide compounding and the American Medical Association on injectable peptides) do not fall into these five categories

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The activation of SIRT1 through increased NAD+ availability improves how cells respond to insulin, facilitating better glucose uptake and utilization

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