glutathione s-transferase function transferases as mediators of signaling pathways involved in cell proliferation and cell death Glutathione S-transferases in kidney and

63 The key role of GSH in DNA synthesis is attributed to the maintenance of reduced glutaredoxin or thioredoxin, which are required for the proper function of ribonucleotide reductase, the rate-limiting enzyme in DNA synthesis

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(Prog Neuropsychopharmacol Biol Psychiatry, 1996) found that IV glutathione (600 mg twice daily for 30 days) improved motor symptoms by 42% on the UPDRS, with benefits lasting 2-4 months [50]

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